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Grandi G. et al.
Efficacy and Safety of CONAN® Proctological Cream Formulation in the Topical Treatment of Haemorrhoidal Disease and Anal Fissures: A Randomized Controlled Clinical Trial.
Minerva Obstetrics and Gynecology (2024) Vol. 76
Giarratano G. et al.
The effect of a flavonoid mixture containing diosmin, hesperidin and troxerutin in women with congestion syndrome associated to pelvic pain: a color Doppler ultrasonography study.
J Surg (2024) 9: 11065
Ballo M.
Efficacia clinica dell’associazione Diosmina, Esperidina e Troxerutina nei pazienti con Malattia Venosa Cronica.
Farmaci 2020 • Volume 19 • N. 2
Sarcinella R. et al.
Linfedema secondario post-mastectomia: riduzioni volumetriche e tissutali in seguito ad utilizzo di benzopironi e flavonoidi associati a linfodrenaggio manuale.
Il Continuum del Paziente Vascolare, 2017
Giannini I. et al.
Flavonoids mixture (diosmin, troxerutin, hesperidin) in the treatment of acute hemorrhoidal disease: a prospective, randomized, triple-blind, controlled trial.
Tech Coloproctol (2015) 19: pp. 339–345
Boccardo F. et al.
Studio sull’efficacia dell’associazione Cumarina, Flavonoidi e Vitexina nel trattamento del Linfedema.
Il Continuum del Paziente Vascolare, 2014
Ballo M. et al.
Trattamento dell’Insufficienza Venosa Cronica. Esperienza clinica con l’associazione diosmina-esperidina-troxerutina.
Il Continuum del Paziente Vascolare, 2014
Bonifacci P. et al.
Utilità della terapia flebotonica ed elastocompressiva nel trattamento dell’edema da stasi venosa.
Il Continuum del Paziente Vascolare, 2010
Morelli C. et al
Effetto biologico di una formulazione a base di diosmina, esperidina e troxerutina (Triade®) sulla permeabilità dell’endotelio vasale umano.
Il Continuum del Paziente Vascolare, 2010
Bartoli M. et al.
Efficacia farmacologica di diversi flebotonici sulla risposta contrattile alla noradrenalina di safene umane isolate.
Il Continuum del Paziente Vascolare, 2010
Ciccone M. et al.
Farmacocinetica della citicolina e della nicotinamide nel ratto dopo somministrazione dell’associazione in soluzione orale (KRON®) e confronto con somministrazione endovenosa
Farmaci 2024, Vol. 23, N.1
Rossetti L., Goni F., Montesano G. et al.
The effect of citicoline oral solution on quality of life in patients with glaucoma: the results of an international, multicenter, randomized, placebo controlled cross over trial.
Graefe’s Arch Clin Exp Ophthalmol. 2023 Jan 14.
Vernazza S. et al.
Citicoline Eye Drops Protect Trabecular Meshwork Cells from Oxidative Stress Injury in a 3D In Vitro Glaucoma Model.
Int. J. Mol. Sci. 2022, 23, 11375.
Rossetti L. et al.
Can Treatment With Citicoline Eyedrops Reduce Progression in Glaucoma? The Results of a Randomized Placebo-controlled Clinical Trial.
J Glaucoma 2020 Jul; 29(7): 513- 20
Sbardella D. et al.
Structural and functional evidence for citicoline binding and modulation of 20S proteasome activity: Novel insights into its pro-proteostatic effect. Biochem
Pharmacol 2020 Jul; 177:113977
Lanza M. et al.
Morphological and Functional Evaluation of Oral Citicoline Therapy in Chronic Open-Angle Glaucoma Patients: A Pilot Study With a 2-Year Follow-Up. Front
Pharmacol. 2019 Sep 26;10:1117
Fogagnolo M. et al.
Topical citicoline and vitamin B12 versus placebo in the treatment of diabetes-related corneal nerve damage: a randomized double-blind controlled trial.
BMC Ophthalmol. 2020;20:315
Parravano M. et al.
Citicoline and VitaminB12 Eye Drops in Type 1 Diabetes: Results of a 3-year Pilot Study Evaluating Morpho-Functional Retinal Changes.
AdvTher (2020)37:1646–1663
Oddone F. et al.
Citicoline in Ophthalmological Neurodegenerative Disease: A Comprehensive Review.
Pharmaceuticals (Basel). 2021 Mar 20;14(3):281
Faiq MA. et al.
Cholinergic nervous system and glaucoma: From basic science to clinical applications.
Prog Retin Eye Res. 2019 Sep;72:100767
Carnevale C. et al.
Human vitreous concentrations of citicoline following topical application of citicoline 2% ophthalmic solution.
PLoS One. 2019; 14(11): e0224982
Parisi V. et al.
Neuroenhancement and neuroprotection by oral solution citicoline in non-arteritic ischemic optic neuropathy as a model of neurodegeneration: A randomized pilot study.
PLoS One. 2019 Jul 26;14(7):e0220435
Parisi V. et al.
Citicoline and Retinal Ganglion Cells: Effects on Morphology and Function.
Current Neuropharmacology, 2018, 16, 919-932
Parisi V. et al.
Enhancement of Retinal Function and of Neural Conduction Along the Visual Pathway Induced by Treatment with Citicoline Eye Drops in Liposomal Formulation in Open Angle Glaucoma: A Pilot Electrofunctional Study.
Adv Ther (2019) 36:987–996
Bogdanov P. et al.
Effects of Liposomal Formulation of Citicoline in Experimental Diabetes-Induced Retinal Neurodegeneration.
Int. J. Mol. Sci. 2018, 19, 2458
Librando A. et al.
Effectiveness of 0.1% topical salicylic acid on blepharoconjunctivitis affecting glaucoma patients treated with topical prostaglandin analogues: a prospective randomized trial.
Int J Ophthalmol, Vol. 11, No. 12, Dec.18, 2018
Nucci C. et al.
Neuroprotective agents in the management of glaucoma.
Eye, 2018 May; 32(5):938-945
Parisi V. et al.
Citicoline and Retinal Ganglion Cells: Effects on Morphology and Function.
Current Neuropharmacology, 2018, 16, 919-932
Oddone F. et al.
Cytidine 5′- Diphosphocholine (Citicoline) in Glaucoma: Rationale of Its Use, Current Evidence and Future Perspectives.
IJMS 2015, 16, 28401–28417
Maestroni S. et al.
In vivo Evaluation of Retinal and Choroidal Structure in a Mouse Model of Long-Lasting Diabetes. Effect of Topical Treatment with Citicoline.
Journal of Ocular Diseases and Therapeutics, 2015, 3, 1-8
Parisi V. et al.
Treatment with citicoline eye drops enhances retinal function and neural conduction along the visual pathways in open angle glaucoma.
Arch Clin Exp Ophthalmol.2015 Aug;253(8):1327-40
Gualdi M. et al.
Efficacia e tollerabilità dell’acido ialuronico associato a citicolina e vitamina B12 sulle alterazioni post-chirurgiche della superficie corneale dopo interventi di cross-linking, prk e femtolasik.
Ottica Fisiopatologica, Anno diciannovesimo settembre 2014
Roberti G. et al.
A preliminary study of the neuroprotective role of citicoline eye drops in glaucomatous optic neuropathy.
Indian J Ophthalmol. 2014 May;62(5):549-53
Matteucci A. et al.
Neuroprotective Effects of Citicoline in in Vitro Models of Retinal Neurodegeneration.
Int. J. Mol. Sci. 2014, 15, 6286-6297
Caprino D. et al.
Valutazione della progressione del danno perimetrico in soggetti con glaucoma iniziale ad angolo aperto tonometricamente compensati e in trattamento con citicolina in soluzione orale.
Ottica Fisiopatologica, Anno diciottesimo giugno 2013
Ottobelli L. et al.
Citicoline Oral Solution in Glaucoma: Is There a Role in Slowing Disease Progression?
Ophthalmologica 2013;229:219–226
Morreale Bubella D. et al.
Neuroprotezione del paziente con Glaucoma cronico ad angolo aperto: ruolo della Citicolina in soluzione orale.
Ottica Fisiopatologica, Anno sedicesimo settembre 2011
Hamann K. U. et al.
Terapia della blefarocongiuntivite con un collirio a base di acido salicilico. (Therapy of Blepharoconjunctivitis with Eye Drops containing salicylic acid).
ZEITSCHRIFT FÜR PRAKTISCHE AUGENHEILKUNDE” 16: 97-100 (1995)